WebDec 2, 2014 · Cisplatin is one of the most widely used and highly effective drug for the treatment of various solid tumors; however, it has dose-dependent side effects on the kidney, cochlear, and nerves. Nephrotoxicity is the … WebOxaliplatin Avoid cold drinks/food during administration Vincristine Loss of deep tendon reflexes Constipation Jaw Pain Paclitaxel Premedicate with Benadryl, dexamethasone and an H2-receptor blocker Etoposide Monitor for hypotension Irinotecan Major side …
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WebCisplatin is a potent and valuable chemotherapy agent used to treat a broad spectrum of malignancies. Renal tubular dysfunction and a cumulative impairment in kidney function, … WebApr 19, 2024 · Cisplatin + etoposide ± doxorubicin ± mitotane Carboplatin + etoposide ± doxorubicin ± mitotane Other recommended regimens Pembrolizumab ± mitotane ... ima prank my dad meme did the kid survive
Cisplatin: Package Insert - Drugs.com
WebResults: We observed an increase in serum creatinine level to a peak of 1.9 mg/dL (range, 0.8 to 7.8) in the dopamine group, in comparison to 1.4 mg/dL (range, 0.9 to 3.3) in the placebo group (P = .04). Urinary magnesium excretion increased and EGF excretion decreased in both groups. WebSep 21, 2024 · electrolyte depletion (for example, sodium, potassium). Other important side effects include: jaundice, ringing in the ears ( tinnitus ), sensitivity to light ( photophobia ), rash, pancreatitis, nausea, diarrhea, abdominal pain, and dizziness. Increased blood sugar and uric acid levels also may occur. WebSep 15, 2024 · Since its approval in 1979 cisplatin has become one of the most extensively used chemotherapeutics in the clinic and although cell resistance and toxicity hinder its efficacy it continues to be a gold standard regimen. Cisplatin's side effects primarily include nephrotoxicity, gastrointestinal toxicity, neurotoxicity and ototoxicity. ima professional protection scheme