WebCitrinin (Figure 5 (b)) is a low-molecular-weight (250.25 g mol −1) compound that has a melting point of 175 °C. Citrinin initially was named as monascidin A and was regarded … WebAug 26, 2006 · Two previously unreported citrinin dimer derivatives, penicitol D (1) and 1-epi-citrinin H1 (2), were isolated from the culture of a deep sea-derived fungus Penicillium citrinum NLG-S01-P1 ...
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WebAug 19, 2010 · However, citrinin H1, as a dimeric product formed upon heating at 140 • C in the presence of water, contributed to an increase in cytotoxicity [5]. Despite its toxic properties, there is ... WebJan 10, 2024 · Two previously unreported citrinin dimer derivatives, penicitol D (1) and 1-epi-citrinin H1 (2), were isolated from the culture of a deep sea-derived fungus …
Web17 1-epi-citrinin H1 18 (3S,4S)-sclerotinin A Vibrio vulnificus and Vibrio campbellii 15-17 µg/ml 19 (3S) -hydroxy 4 epi isosclerone 20 Suberea sp. in Wakatobi National Park Mycobacterium Penicitrinone A M. smegmatis 32 µg/ml [24] 21 Penicitrinols J Bacillus sublitis, Bacillus megaterium, smegmatis 16, 16, and 32 µg/ml WebIn this work we are reporting the isolation by classical methods of chromatography of six polyketides from Penicillium herquei.The compounds citreorosein ( 1) , emodin ( 2) , janthinone ( 3) , citrinin ( 4) , citrinin H1 ( 5) and dicitrinol ( 6) were identified by spectral methods of 1D and 2D NMR and MS. Compounds 1, 2 and 3 were tested against …
WebMar 23, 2012 · Citrinin is nephrotoxic and a no-observed-adverse-effect level (NOAEL) of 20 µg/kg body weight (b.w.) per day was identified from a 90-day study in rats. Due to the limitations and uncertainties in the database, the derivation of a health-based guidance value was not considered appropriate but a level of no concern for nephrotoxicity of 0.2 ... WebSep 17, 2013 · Open in a separate window. Penicillium citrinum is one of the commonest microfungi on Earth, occurring in all kinds of food and feed, in almost all climates. CIT is produced over the range of 15–30 °C and optimally at 30 °C. Penicillium expansum is known as a postharvest pathogen of fruits (e.g., apple) and vegetables.
WebOct 1, 2024 · Due to the rotatability of the groups on the chain, the relative configuration of the group on the chain cannot be determined. Considering the postulated dimeric mechanism for citrinin H1 (Trivedi et al., 1993; Wang et al., 2024), the configuration of the two methyl groups located in C-7′ and C-8′ was determined to be trans.
Webdouble strand H0−H1 structure. Because of the complemen-tary sequences between H1 and H2, strand displacement occurs as soon as the double strand H0−H1 is formed. … how are tungsten electrodes color codedWebJan 1, 2015 · citrinin H1, from citrinin on mild heating in water. Journal of the Chemical . Society Perkin Transactions 1: 2167-2171. 23. Clark BR, … how many minutes are in a quarter hourWebJan 23, 2024 · Chemical structures of citrinin and its decomposition products citrinin H1 and citrinin H2. CIT is synthesized via the polyketide pathway [20]. It is generally known that three . how many minutes are in college basketballWebCitrinin is one of the mycotoxins produced by Penicillium citrinum. We examined the decomposition products after heating citrinin in water at 140 degrees C and isolated a … how many minutes are in a nba quarterWebOct 9, 2024 · Citrinoids are BQs associated with the citrinin (33) biosynthetic pathway and include citrinin H1 (34) and its stereoisomer 1-epi-citrinin H1. Citrinin (33) itself is not a quinone, but citrinin H1 (34) can be synthesized by heating molecules of citrinin in water (Trivedi et al. 1993) and has also been discovered in P. citrinum (section Citrina ... how many minutes are in a leap yearWebAug 19, 2010 · However, citrinin H1, as a dimeric product formed upon heating at 140 • C in the presence of water, contributed to an increase in cytotoxicity [5]. Despite its toxic … how many minutes are in a year with 365 daysCitrinin H1 is produced out of two citrinin molecules and its toxicity is increased compared to the original toxicity of citrinin. Citrinin H2, a formylated derivative of phenol A, is less toxic than citrinin. Phenol A seems to be produced mainly under acidic conditions. Dicitrinin A is a dimer of citrinin molecules … See more Citrinin is a mycotoxin which is often found in food. It is a secondary metabolite produced by fungi that contaminates long-stored food and it causes different toxic effects, like nephrotoxic, hepatotoxic and cytotoxic effects. … See more Citrinin was one of the many mycotoxins discovered by H. Raistrick and A.C. Hetherington in the 1930s. In 1941 H. Raistrick and G. Smith identified citrinin to have a broad antibacterial activity. After this discovery the interest in citrinin rose. However, in 1946 … See more The existing information on occurrence of citrinin in food suggests that relatively high citrinin concentrations can be found in stored grains and … See more Citrinin is biosynthesized by fungi species of Penicillium, Monascus and Aspergillus. For the production of citrinin, a minimal set of genes is needed. These genes are conserved in most … See more Citrinin is a polyketide mycotoxin, which is a secondary metabolite of some fungi species. Its IUPAC name is (3R,4S)-4,6-dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-3H-2-benzopyran-7-carboxylic acid and the molecular formula is C13H14O5. Citrinin has a … See more There are different types of toxicity. The types of toxicity that have been studied for citrinin are acute toxicity, nephrotoxicity, genotoxicity See more Various in vitro studies have revealed the involvement of citrinin toxicity in reduced cytokine production, inhibition of RNA and DNA synthesis, induction of oxidative stress, inhibition of nitride oxide gene expression, increase in ROS production and activation of … See more how many minutes are in february