Ctgf and cyr61
WebBackground The CCN genes encode secreted extracellular matrix proteins cysteine rich-61 (Cyr61), connective tissue growth factor (CTGF) and nephroblastoma overexpressed (Nov). They are involved in diverse cellular functions. Expression of these factors in tumours has produced conflicting results. More recently, research has focused on molecular … WebJun 20, 2007 · Our results suggest that Cyr61, CTGF, and WISP-1might be implicated in the development and progression of primary lung cancers, and their levels might serve as valuable prognostic markers, as well as potential targets for therapeutic intervention. Introduction Lung cancer is the most common cause of cancer death in the world [1].
Ctgf and cyr61
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WebThe penile expression levels of YAP, TAZ, CTGF, and CYR61 were significantly downregulated in the BCNI group (p<0.01), and LIPUS upregulated the expression levels of these proteins (p<0.05). The expression levels of p-LATS1 and LATS1 were not significantly different among the groups (p>0.05). Interestingly, the expression level of p-p38/p38 ... http://www.worldjour.net/Article/show/id/184.html
WebFeb 21, 2014 · The Cyr61/CTGF/Nov (CCN) proteins are a family of matricellular proteins with variable roles in many physiological and pathological processes. The evidence … WebApr 1, 2024 · Human polyclonal anti-rabbit CYR61, CTGF, and dCK antibodies and polyclonal goat anti-rabbit IgG-HRP and monoclonal goat anti-mouse IgG-HRP were …
WebJun 7, 2024 · The transcriptional co-activator Yes-associated protein (YAP; also known as YAP1) is a major downstream effector of the Hippo signaling pathway (Wang et al., … WebBackground The CCN genes encode secreted extracellular matrix proteins cysteine rich-61 (Cyr61), connective tissue growth factor (CTGF) and nephroblastoma overexpressed …
WebMar 3, 2004 · Upper right panel: reverse transcription-polymerase chain reaction analysis for CTGF and Cyr61 mRNAs. The 500-base-pair coding regions of CTGF and Cyr61 cDNA were used as probes. A ß-actin probe was used as an internal control for RNA quantity. Lower panel: The invasion activity of each clone was measured in vitro with the Boyden … citb client based approachFull-length CYR61 protein contains 381 amino acids with an N-terminal secretory signal peptide followed by four structurally distinct domains. The four CYR61 domains are, from N- to C-termini, the insulin-like growth factor binding protein (IGFBP) domain, von Willebrand type C repeats (vWC) domain, thrombospondin type 1 repeat domain (TSR), and the C-terminal (CT) domain that contains a c… citb community benefits tableWebNational Center for Biotechnology Information citb companies houseWebConnective tissue growth factor (CTGF) is a member of the recently described CCN gene family which contains CTGF itself, cyr61, nov, elm1, Cop1, and WISP-3. CTGF is transcriptionally activated by several factors although its stimulation by transforming growth factor beta (TGF-beta) has attracted considerable attention. citb clydebankWebCYR61 and CTGF can also bind to integrin α 6 β 1 on fibroblasts, stimulating proliferation and migration of fibroblasts. The matrix-stimulating activity of CTGF, combined with the … citb companyWebConnective tissue growth factor (CTGF), also termed fisp12, β IG-M2, and IGF-BP8, is a secreted cysteine-rich growth factor that belongs to the CCN (cyr61, CTGF, nov) family. It was first isolated in 1991 from serum-stimulated NIH3T3 cells and named fisp12 (fibroblast-inducible secreted protein-12). The term ‘connective tissue growth factor ... citb community benefitsWebYAP, CTGF and Cyr61 are overexpressed in tamoxifen-resistant breast cancer and induce transcriptional repression of ERα. Hyungjoo Kim. 1, Seogho Son1, Yunhyo Ko1, Jeong Eon Lee3, Sangmin Kim3 ... citb commissioning team