Solubility of gemcitabine hydrochloride

Author: vynn

August undefined, 2024

WebGemcitabine HCl (Gemzar) ... *<1 mg/ml means slightly soluble or insoluble. *Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and … WebApr 1, 1999 · Gemcitabine is a fluoro-cytidine analog with primarily antitumor activity and is administered intravenously [120]. Although its hydrochloride salt is well soluble in water …

Gemcitabine hydrochloride (CAS 122111-03-9): R&D …

WebBiological Activity for Gemcitabine hydrochloride. Gemcitabine hydrochloride is a deoxycytidine analog that inhibits DNA synthesis. Metabolized to form gemcitabine … WebSolubility: Soluble in DMSO at 12.5 mg/mL with slight warming; very poorly soluble in ethanol; soluble in water at 25 mg/mL with slight warming; buffers, ... Gemcitabine … irish stuffed cabbage wraps

Gemcitabine: Package Insert - Drugs.com

WebGemcitabine Hydrochloride is the hydrochloride salt of an analogue of the antimetabolite nucleoside deoxycytidine with antineoplastic activity. … WebApr 1, 1999 · Reconstituted gemcitabine as the hydrochloride salt in the original vials is chemically stable at room temperature for 35 days but may develop crystals when stored … WebGemcitabine, HCl - CAS 122111-03-9 - Calbiochem. View Price and Availability. Supelco. PHR2582. Gemcitabine hydrochloride. Pharmaceutical Secondary Standard; Certified … irish style farmhouse vegetable soup

Gemcitabine hydrochloride = 98 HPLC 122111-03-9 - Sigma-Aldrich

Gemcitabine Hydrochloride CAS 122111-03-9 - SCBT

WebMar 1, 2024 · One vial contains Gemcitabine hydrochloride equivalent to 200 mg Gemcitabine One vial contains Gemcitabine hydrochloride equivalent to 1000 mg Gemcitabine . After reconstitution, the solution contains 38 mg/ml of Gemcitabine. Excipients: Each 200 mg vial contains 3.5 mg (<1 mmol) sodium. Each 1,000 mg vial … WebName Gemcitabine hydrochloride Drug Entry Gemcitabine. Gemcitabine is a nucleoside analog and a chemotherapeutic agent. It was originally investigated for its antiviral … irish style homes exteriorWebGemcitabine hydrochloride is a deoxycytidine analog that inhibits DNA synthesis. Metabolized to form gemcitabine triphosphate (dFdCTP) and gemcitabine diphosphate ... port family medical group

"WebFeb 25, 2024 · The solution was then diluted 10× with a premade PBS solution of gemcitabine (hydrochloride salt) (12.65 mg/mL). Final concentrations of drugs were 10/1 mg/mL GT. CrEL drug suspensions were used within the same day of preparation due to instability. ... Whether a water soluble gemcitabine (Log P=−1.5) and insoluble paclitaxel ... " - Solubility of gemcitabine hydrochloride

Solubility of gemcitabine hydrochloride

Gemcitabine hydrochloride = 98 HPLC 122111-03-9

WebGemcitabine hydrochloride (2′-Deoxy-2′,2′-difluorocytidine; dFdC ); >= 98% HPLC; This compound is a featured product for Apoptosis research; Gemcitabine is a widely used antineoplastic agent and antimetabolite; Gemcitabine is a widely used antitumor agents in both clinics and research labs; WebJun 1, 2024 · Gemcitabine hydrochloride is soluble in water, slightly soluble in methanol, and practically insoluble in ethanol and polar organic solvents. Gemcitabine for Injection, USP is a sterile white to off-white lyophilized powder and available as 200 mg and 1 g single-dose vials for intravenous use only.

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WebJun 29, 2024 · Gemcitabine 1 g/m 2 (as 30-minute infusion) has been given on days 1 and 8 of each 21-day cycle; administered in combination with cisplatin (25 mg/m 2 as 1-hour … WebGemcitabine hydrochloride (2′-Deoxy-2′,2′-difluorocytidine; dFdC ); >= 98% HPLC; This compound is a featured product for Apoptosis research; Gemcitabine is a widely used …

http://shiji.cnreagent.com/s/sv273316.html WebApr 10, 2024 · Erlotinib’s aqueous solubility is pH-dependent; it is less soluble at neutral pH but more soluble at acidic pH (~ below 5). Erlotinib HCl, marketed under the brand name Tarceva, is prescribed as a single film-coated orally administered tablet at strengths of 25–125. Erlotinib HCL has a maximum solubility of around 0.4 mg/mL at a pH of ~ 2 .

WebDec 2, 2013 · The release behavior of another anti-cancer drug gemcitabine from the PU matrix is quite different from that of PTX due to the extreme difference in water solubility between gemcitabine and PTX.PTX is practically insoluble in water, whereas gemcitabine is readily soluble in water and has a solubility of 1.55% [37,67]. WebApplication. It is intended to be used as a USP reference standard in specified quality tests and assays. Also used to prepare standard solutions in the assay and impurities analysis …

WebGemcitabine prepared as intravenous admixtures of 0.1 and 10 mg/mL as the hydrochloride salt in 5% dextrose injection and 0.9% sodium chloride injection in PVC bags and as a … irish style number platesWebUse in Cancer. Gemcitabine hydrochloride is approved to be used alone or with other drugs to treat: Breast cancer that cannot be treated with or that did not respond to … irish style hats for menWebTest conditions included (1) reconstituted gemcitabine at a concentration of 38 mg/mL as the hydrochloride salt in 0.9% sodium chloride or sterile water for injection in the original … port farms waterford pennsylvaniaWebGeneral description. A bioavailable, moderately toxic, deoxyctytidine analog with anti-metabolite and anti-tumor properties. Shown to be effective against a variety of tumors … irish style banoffee pieWebGemcitabine (LY-188011, NSC 613327) HCl is a DNA synthesis inhibitor with IC50 of 50 nM, 40 nM, 18 nM and 12 nM in PANC1, MIAPaCa2, BxPC3 and Capan2 cells, respectively. … port family medicineWebJun 1, 2024 · Gemcitabine hydrochloride is soluble in water, slightly soluble in methanol, and practically insoluble in ethanol and polar organic solvents. Gemcitabine for Injection, … irish sufi foundationWebGemcitabine hydrochloride (2′-Deoxy-2′,2′-difluorocytidine; dFdC ); >= 98% HPLC; This compound is a featured product for Apoptosis research; Gemcitabine is a widely used … irish style wedding dress